发明名称 |
INDANYL-PIPERAZINE COMPOUND, ITS PRODUCTION METHOD AND MEDICINAL COMPOSITION CONTAINING IT |
摘要 |
PROBLEM TO BE SOLVED: To provide a new inhibitor of serotonin reuptake and an NK<SB>1</SB>antagonist. SOLUTION: A compound represented by formula (I): [wherein, one of R<SB>1</SB>and R<SB>3</SB>indicates a hydrogen atom and the other combines with R<SB>2</SB>to form a ring such as benzene or naphthalene; n indicates 1 or 2; -X- indicates -CH<SB>2</SB>-O-CH<SB>2</SB>-, -CH<SB>2</SB>-NH-CH<SB>2</SB>-, -CONH-CH<SB>2</SB>- or the like; and Ar indicates an aryl or heteroaryl group], its optical isomer and its pharmaceutically acceptable salt adduct with an acid are provided. COPYRIGHT: (C)2007,JPO&INPIT
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申请公布号 |
JP2006282669(A) |
申请公布日期 |
2006.10.19 |
申请号 |
JP20060093025 |
申请日期 |
2006.03.30 |
申请人 |
LAB SERVIER |
发明人 |
DE NANTEUIL GUILLAUME;PORTEVIN BERNARD;GLOANEC PHILIPPE;MILLAN MARK;ORTUNO JEAN-CLAUDE;MANNOURY LA COUR CLOTILDE;GOBERT ALAIN |
分类号 |
C07D213/40;A61K31/495;A61K31/496;A61P1/04;A61P1/08;A61P3/04;A61P25/00;A61P25/02;A61P25/04;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P29/00;A61P43/00;C07D213/61;C07D295/08;C07D295/12;C07D295/14;C07D333/20 |
主分类号 |
C07D213/40 |
代理机构 |
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地址 |
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