发明名称 (3,4-DIHYDRO-QUINAZOLIN-2-YL)-INDAN-1-YL-AMINES
摘要 <p>The present invention relates to compounds of formula (I) wherein R1 is hydrogen, lower alkyl, lower alkoxy, halogen or lower alkyl substituted by halogen; R2 is hydrogen, lower alkyl, aryl or hetaryl, wherein aryl and hetaryl may be optionally substituted by one or more substituents selected from the group consisting of lower alkyl or halogen; n is 1 or 2; and to pharmaceutically acceptable acid addition salts thereof. It has been found that the compounds of formula I have a good activity on the 5-HT5A receptor. Therefore, the invention provides the use of a compound of formula I for 5-HT5Areceptor related diseases.</p>
申请公布号 WO2006108773(A1) 申请公布日期 2006.10.19
申请号 WO2006EP61279 申请日期 2006.04.03
申请人 F. HOFFMANN-LA ROCHE AG;ALANINE, ALEXANDER;GOBBI, LUCA CLAUDIO;KOLCZEWSKI, SABINE;LUEBBERS, THOMAS;PETERS, JENS-UWE;STEWARD, LUCINDA 发明人 ALANINE, ALEXANDER;GOBBI, LUCA CLAUDIO;KOLCZEWSKI, SABINE;LUEBBERS, THOMAS;PETERS, JENS-UWE;STEWARD, LUCINDA
分类号 C07D239/84;A61K31/517;A61P25/24 主分类号 C07D239/84
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