| 摘要 |
The present invention provides for compounds of formula (I), (Ia) and (Ib) Wherein: A is selected from C-X and N, B is selected from C-Y and N, R<SUP>1 </SUP>is selected from H and (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, R<SUP>2 </SUP>is selected from H and (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, X is selected from H, HO, C(O)NH<SUB>2</SUB>, NH<SUB>2 </SUB> Y is selected from H, HO, NH<SUB>2</SUB>, Br, Cl and F Z is selected from H, HO F, CONH<SUB>2 </SUB>and CN; And pharmaceutically acceptable salts, solvates and prodrugs thereof; With the provisos that: for a compound of formula (I), (Ia) or (Ib), when A is C-X, B is C-Y, R<SUP>1 </SUP>is H or (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl and R<SUP>2 </SUP>is H or (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl at least one of X, Y and Z must be OH; for a compound of formula (I), when A is C-X and B is C-Y, Y is H, Z is H, R<SUP>1 </SUP>is H and R<SUP>2 </SUP>is H, then X cannot be OH; these compounds are useful as a medicament.
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