发明名称 |
Process for the preparation of gabapentin form-II |
摘要 |
The present invention relates to a new industrial feasible process for the preparation of Gabapentin Form-II via a novel intermediate Gabapentin hemisulphate hemihydrate with out forming Gabapentin Form-III by neutralizing the Gabapentin hemisulphate hemihydrate solution with a base at higher temperatures followed by cooling to yield Gabapentin Form II with sulphate ions less than 100 ppm with respect to Gabapentin.
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申请公布号 |
US2006235079(A1) |
申请公布日期 |
2006.10.19 |
申请号 |
US20050553821 |
申请日期 |
2005.10.19 |
申请人 |
CHAVA SATYANARAYANA;GORANTLA SEETA R;INDUKURL VENKATA S K |
发明人 |
CHAVA SATYANARAYANA;GORANTLA SEETA R.;INDUKURL VENKATA S.K. |
分类号 |
A61K31/195;A61K;C07C227/04;C07C227/06;C07C227/20;C07C227/40;C07C227/42;C07C229/28 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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