PROCESS OF MANUFACTURING VIRAL VACCINES IN SUSPENSION AVIAN EMBRYONIC DERIVED STEM CELL LINES

摘要

The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx cell line derived from chicken embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals.