| 摘要 |
The present invention concerns the field of integrative analysis of molecular interactions in a biological system. In particular, it pertains to a method for obtaining a dynamic model of a molecular interaction network in a biological system that allows analysis of said interactions when a stimulus is applied to the dynamic model, with a view in particular of hierarchizing biological molecules or selecting therapeutic targets in respect of a given biological problem, in particular to define a therapeutic action to be applied to said molecules. The invention also pertains to an informatics system for producing a dynamic model of a molecular interaction network in a biological system, and analyzing said molecular interactions when a stimulus is applied to the dynamic model, the informatics system comprising at least one central data processing unit connected to at least one quantitative experimental database.
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