摘要 |
The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second stretch Box B, whereby the first stretch Box A comprises about 25 consecutive nucleotides, the second stretch Box B comprises about six to eight consecutive nucleotides, whereby a 3'-terminal stretch of nucleotides of the first stretch Box A hybridises with the second stretch Box B, whereby upon hybridisation a first double-stranded structure is formed, whereby such first double-stranded structure comprises a bulge. |
申请人 |
NOXXON PHARMA AG;JAROSCH, FLORIAN;EULBERG, DIRK;MAASCH, CHRISTIAN;HELMLING, STEFFEN;KLUSSMANN, SVEN |
发明人 |
JAROSCH, FLORIAN;EULBERG, DIRK;MAASCH, CHRISTIAN;HELMLING, STEFFEN;KLUSSMANN, SVEN |