发明名称 |
Method for treating oncological diseases |
摘要 |
The invention relates to medicine and veterinary science and can be used for treating mainly solid tumors. The inventive method for treating oncological diseases consisting in injecting a blood extracellular DNA destroying agent into a systemic blood circulation. Said blood extracellular DNA destroying agent can be embodied in the form of a DNAse enzyme, in particular a bovine pancreatic DNAse which is parenterally injected in doses ranging from of 50 000 Kunz units to 250 000 000 Kunz units a day every day during 5-360 days or in the form of a recombinant human DNAse. In addition, a blood extracellular DNA binding agent embodied in the form of anti-DNA antibodies can be injected into a systemic blood circulation. In addition a modified agent which modifies the chemical composition and/or conformation and/or polymery and/or an association with proteins and/or lipids and/or ribonucleic acids of the blood extracellular DNA. Said modifying agent can be embodied in the form of a enzyme-ribonuclease. An extracellular ribonuclease of a Serratia Mercenses bacterium can be used in the form of said agents.
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申请公布号 |
US2006233780(A1) |
申请公布日期 |
2006.10.19 |
申请号 |
US20060564861 |
申请日期 |
2006.01.12 |
申请人 |
GENKIN DMITRY D;TETS VIKTOR V;TETS GEORGY V |
发明人 |
GENKIN DMITRY D.;TETS VIKTOR V.;TETS GEORGY V. |
分类号 |
A61K38/43;A61K38/46;A61K38/44;A61P35/00;C12N9/22 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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