The invention relates to the compound apogossypolone and salts and prodrugs thereof. Apogossypolone functions as an inhibitor of Bcl-2 family proteins. The invention also relates to the use of apogossypolone for inhibiting hyperproliferative cell growth, for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.
申请公布号
WO2006050447(A3)
申请公布日期
2006.10.19
申请号
WO2005US39704
申请日期
2005.11.02
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;WANG, SHAOMENG;NIKOLOVSKA-COLESKA, ZANETA;YANG, CHAO-YIE;CHEN, JIANYONG
