<p>Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise oligonucleotides, targeted to nucleic acid encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for diagnosis and treatment of diseases and conditions associated with expression of glucocorticoid receptor are provided.</p>
申请公布号
EP1711606(A2)
申请公布日期
2006.10.18
申请号
EP20050722546
申请日期
2005.01.20
申请人
ISIS PHARMACEUTICALS, INC.
发明人
BHANOT, SANJAY;DOBIE, KENNETH, W.;FREIER, SUSAN, M.;DEAN, NICHOLAS, M.;BENNETT, C., FRANK