发明名称 INTRAVASCULAR DELIVERY OF NUCLEIC ACID
摘要 <p>Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian blood vessel. Prior to insertion, subsequent to insertion, or concurrent with insertion the permability of the vessel is increased using an exterior cuff and immunosuppression is applied thereby the genetic material is delivered to the parenchymal cell.</p>
申请公布号 EP1246649(B1) 申请公布日期 2006.10.18
申请号 EP20000976999 申请日期 2000.11.06
申请人 MIRUS BIO CORPORATION 发明人 WOLFF, JON, A.
分类号 A61K48/00;A61B5/02;A61B17/132;A61K38/12;C12N15/87 主分类号 A61K48/00
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