发明名称 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE
摘要 The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing theses compounds.
申请公布号 EP1711515(A2) 申请公布日期 2006.10.18
申请号 EP20050712717 申请日期 2005.02.04
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 COTTRELL, KEVIN, M.;COURT, JOHN, J.;DEININGER, DAVID, D.;FARMER, LUC, J.;PITLIK, JANOS;PERNI, ROBERT B.
分类号 C07K7/02;A61K38/00;A61K38/04;A61K38/05;A61K38/07;A61K38/08;C07K5/02;C07K5/04;C07K14/18 主分类号 C07K7/02
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