发明名称 |
Methods of producing peptides/proteins in plants and peptides/proteins produced thereby |
摘要 |
Methods of increasing the yield in plant expression of recombinant proteins comprising: engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed. |
申请公布号 |
EP1711533(A2) |
申请公布日期 |
2006.10.18 |
申请号 |
EP20050726258 |
申请日期 |
2005.01.14 |
申请人 |
OHIO UNIVERSITY |
发明人 |
KIELISZEWSKI, MARCIA, J.;XU, JIANFENG;KOPCHICK, JOHN;OKADA, SHIGERU |
分类号 |
C12N15/82;C07H21/00;C07H21/02;C07H21/04;C07K14/415;C07K14/61;C07K14/765;C07K19/00;C12N15/62;C12P21/00 |
主分类号 |
C12N15/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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