Tricyclic indole derivatives and their use in the treatment of alzheimer's disease

摘要

The present invention to novel hydroxyethylamine compounds having Asp2 (beta-secretase, BACE1 or Memapsin) inhibitory activit, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated beta-amyloid levels or beta-amyloid deposits, Particularly Alzheimer's disease.