发明名称 |
1,5 AND 1,4-ANHYDROKETOSES, METHODS FOR THE PREPARATION OF 1,5-AND 1,4-ANHYDROKETOSES, INTERMEDIATES, AND USES OF 1,5-AND 1,4-ANHYDROKETOSES |
摘要 |
The present invention relates to 1,4- and 1,5-anhydro-D-ketoses (monosaccharides, oligosaccharides and various glycoconjugates), e.g. 1,5-anhydro-D-fructose. Moreover, the invention provides synthetic methods and novel intermediates and precursors suitable for their preparation. The methods include catalytic- and/or pyrolitic sulfenic acid elimination of corresponding ß-hydroxy sulfoxides, N-deprotection of N-substituted-aminoglycals, O-deprotection of carbohydrate enolethers and/or O-acyl-substituted carbohydrate enols, and regio- and stereoselective modification and subsequent chemical transformation of bicyclic and/or tricyclic 1,4- and 1,5-anhydro-glycoderivatives. Furthermore, the present invention provides novel applications of 1,4- and 1,5-anhydroketoses within pharmaceutical, food and cosmetic industries. |
申请公布号 |
WO2005121114(A3) |
申请公布日期 |
2006.10.12 |
申请号 |
WO2005DK00377 |
申请日期 |
2005.06.07 |
申请人 |
GLYCOM APS;LUNDT, INGE;STUETZ, ARNOLD;DEKANY, GYULA;THIEM, JOACHIM;AGOSTON, KAROLY;ANDREASSEN, MIKKEL |
发明人 |
LUNDT, INGE;STUETZ, ARNOLD;DEKANY, GYULA;THIEM, JOACHIM;AGOSTON, KAROLY;ANDREASSEN, MIKKEL |
分类号 |
C07D309/30;C07D493/08;C07D493/18 |
主分类号 |
C07D309/30 |
代理机构 |
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