摘要 |
<p>The present invention relates to novel pyridyl-lactams, compounds of the formula (I), wherein R<SUP>1</SUP> is a group of the formula G<SUP>1</SUP>, G<SUP>2</SUP>, G<SUP>3</SUP> or G<SUP>4</SUP> depicted below, and R<SUP>3</SUP>, Y, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>13</SUP>, a, n and m are as defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions, their preparation and intermediates therefrom, and their use in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which a 5-HT<SUB>1B</SUB> antagonist is indicated.</p> |