发明名称 |
METHOD OF FORMING AN AEROSOL FOR INHALATION DELIVERY |
摘要 |
<p>The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 °C/s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 µ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.</p> |
申请公布号 |
WO02098389(A8) |
申请公布日期 |
2006.10.12 |
申请号 |
WO2002US15425 |
申请日期 |
2002.05.13 |
申请人 |
ALEXZA MOLECULAR DELIVERY CORPORATION |
发明人 |
HALE, RON, L.;HODGES, CRAIG, C.;LLOYD, PETER, M.;MUFSON, DANIEL;ROGERS, DANIEL, D.;SONG, SOONHO;WENSLEY, MARTIN, J.;MYERS, DANIEL J.;MCKINNEY, JEFFREY, A.;QUINTANA, REYNALDO, J.;RABINOWITZ, JOSHUA, D. |
分类号 |
A61K9/72;A61M15/00;A61K9/00;A61K9/16;A61K31/4468;A61M11/00;A61M11/04;A61M16/00;A61P23/00;B05B7/16;B05B17/04 |
主分类号 |
A61K9/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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