发明名称 |
COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS |
摘要 |
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively. |
申请公布号 |
EP1708689(A2) |
申请公布日期 |
2006.10.11 |
申请号 |
EP20040815842 |
申请日期 |
2004.12.29 |
申请人 |
THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE GENERAL HOSPITAL CORPORATION DOING BUSINESS AS MASSACHUSETTS GENERAL HOSPITAL |
发明人 |
SINCLAIR, DAVID, A.;ALEXANDER-BRIDGES, MARIA;BAUR. JOSEPH,A. |
分类号 |
A61K31/00;A61K31/05;A61K31/12;A61K31/353;A61K31/7048 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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