| 发明名称 |
Pharmaceutically active compounds and methods of use thereof |
| 摘要 |
The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.
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| 申请公布号 |
US7119095(B2) |
申请公布日期 |
2006.10.10 |
| 申请号 |
US20040848094 |
申请日期 |
2004.05.17 |
| 申请人 |
DANA FARBER CANCER INSTITUTE |
发明人 |
ROSOWSKY ANDRE;FORSCH RONALD A. |
| 分类号 |
C07D239/48;A61K31/506;A61K31/517;A61K31/519;A61P31/04;A61P31/06;A61P31/08;A61P31/18;A61P33/02;A61P33/06;A61P33/08;C07D239/49;C07D239/95;C07D471/04 |
主分类号 |
C07D239/48 |
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