Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses

摘要

Disclosed are compounds of formula (I): wherein the variables R₁, R₂, R₃ and Z are described herein, which are useful as inhibitors of the kinase activity of the IkappaB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.