发明名称 AT4 receptor ligands as angiogenic, anti-angiogenic, and anti-tumor agents
摘要 AT<SUB>4 </SUB>receptor agonists are potent activators of angiogenesis and can be used to treat diseases that are characterized by vascular insufficiency. AT<SUB>4 </SUB>receptor antagonists, which are potent inhibitors of angiogenesis, and can be used as anti-angiogenic agents for the treatment of cancer, diabetic retinopathy, rheumatoid arthritis, psoriasis, atherosclerotic plaque formation, and any disease process that is characterized by excessive, undesired or inappropriate angiogenesis or proliferation of endothelial cells.
申请公布号 US7118747(B2) 申请公布日期 2006.10.10
申请号 US20030675470 申请日期 2003.09.30
申请人 WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION 发明人 HARDING JOSEPH W;WRIGHT JOHN W
分类号 A61K39/00;A61K38/00;A61K38/05;A61K38/06;A61K38/07;A61K38/08 主分类号 A61K39/00
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