| 发明名称 |
Heteroarylakanoic acids as intergrin receptor antagonists |
| 摘要 |
The present invention relates to a class of compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of Formula (I), and methods of selectively antagonizing the alphanubeta<SUB>3 </SUB>and/or the alphanubeta<SUB>5 </SUB>integrin without significantly antagonizing the IIb/IIIa integrin.
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| 申请公布号 |
US7119098(B2) |
申请公布日期 |
2006.10.10 |
| 申请号 |
US20030311385 |
申请日期 |
2003.09.05 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
NAGARAJAN SRINIVASAN RAJ;KHANNA ISH KUMAR;TOLLEFSON MICHAEL B.;MOHLER SCOTT B.;CHEN BARBARA B.;RUSSELL MARK;DEVADAS BALEKUDRU;PENNING THOMAS D.;SCHRETZMAN LORI A.;SPANGLER DALE P.;BOYS MARK L.;CHANDRAKUMAR NIZAL S.;LU HWANG-FUN |
| 分类号 |
C07D403/12;A61K31/4245;A61K31/4375;A61K31/443;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/496;A61K31/5383;A61P3/14;A61P9/00;A61P9/08;A61P9/10;A61P19/02;A61P19/10;A61P21/00;A61P27/02;A61P35/00;A61P43/00;C07D213/74;C07D231/38;C07D233/60;C07D233/88;C07D401/12;C07D403/14;C07D405/12;C07D413/06;C07D413/12;C07D413/14;C07D417/12;C07D471/04;C07D498/04 |
主分类号 |
C07D403/12 |
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