| 摘要 |
The present invention relates to a pharmaceutical composition characterized in that it contains an active ingredient comprising two or more flavonoids in microcrystalline form, wherein the two or more microcrystalline flavonoids comprise diosmin and at least one other flavonoid; and further wherein the two or more microcrystalline flavonoids exhibit the following characterizing parameters :
(a) a specific surface area of 4 to 18 m 2 /g, according to BET determination;
(b) an F/D (F=other flavonoids/D=diosmin) (weight/weight) ratio of from 0.03 to 0.1; and
(c) a moisture content of less than 4.0 % by weight.
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