NON-SPREADING PESTIVIRUS

摘要

The invention relates to vaccines used in the eradication or control of pestivirus infections, particularly those used in pigs or ruminants. The invention provides nucleic acid, pestivirus-like particles and a pestivirus vaccine, comprising said nucleic acid or particles, which is capable to elicit a proper immune response without having the ability to spread throughout the vaccinated animal, thereby avoiding the negative consequences of viral spread. Preferably said immune response allows for serological discrimination between vaccinated animals and wild-type pestivirus infected animals.