发明名称 METHOD OF INTRACELLULAR BINDING OF TARGET MOLECULES
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for the intramolecular binding of a specific molecule, preferably a protein. <P>SOLUTION: (1) A vector system for the intracellular binding of a specific antigen (target antigen), which comprises a nucleotide sequence adapted to delivery and expression in cells and containing a promoter operably bound to an antibody gene encoding an antibody capable of being bound to the target antibody. In one embodiment, the antibody gene encodes a single strand variable fragment, a single domain H chain, or Fab, and the target antigen is selected from the antigen group consisting of intermediate metabolites, saccharides, lipids, autacoids, hormones, complex carbohydrates, phospholipids, nucleic acids and proteins. <P>COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006254919(A) 申请公布日期 2006.09.28
申请号 JP20060121368 申请日期 2006.04.25
申请人 DANA FARBER CANCER INST INC 发明人 MARASCO WAYNE A;HASELTINE WILLIAM A
分类号 C12N15/09;A61K35/76;A61K39/12;A61K39/29;A61K39/395;A61K48/00;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/04;C07K16/08;C07K16/10;C07K16/18;C07K16/26;C07K16/28;C07K16/32;C07K16/44;C12N5/00;C12N5/10;C12R1/91 主分类号 C12N15/09
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