发明名称 INHIBITION OF APOPTOSIS USING INTERLEUKIN-1BETA-CONVERTING ENZYME (ICE)/CED-3FAMILY INHIBITORS
摘要 <p><P>PROBLEM TO BE SOLVED: To provides a method for expanding and increasing the survival of hematopoietic cell populations (groups comprising granulocytes, monocytes, erythrocytes, lymphocytes and platelets), to provide a method for prolonging viability of an organ for transplantation, and to provide a method for enhancing bioproduction. <P>SOLUTION: This method for inhibiting the apoptosis of hematopoietic cell populations with interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors (nucleic acids, antisense sequences, protease inhibitors). Thereby, the survival of the hematopoietic cell populations can be expanded or increased. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p>
申请公布号 JP2006257096(A) 申请公布日期 2006.09.28
申请号 JP20060132038 申请日期 2006.05.11
申请人 IDUM PHARMACEUTICALS INC 发明人 FRITZ LAWRENCE C;TOMASELLI KEVIN J
分类号 A61K45/00;C12Q1/68;A01N1/02;A61K31/404;A61K31/55;A61K31/7088;A61K38/00;A61K38/55;A61K48/00;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P7/04;A61P7/06;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P21/04;A61P25/00;A61P25/28;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P43/00;C07K5/02;C12N5/06 主分类号 A61K45/00
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