摘要 |
The present invention concerns s-SHIP promoter and developmental decision promoter compositions and methods of using the promoter. It includes polynucleotides, vectors, host cells, and transgenic animal including a developmental decision promoter, for example, an s-SHIP promoter, controlling the expression of a heterologous nucleic acid. Methods of the invention concern methods of expressing a heterologous nucleic acid is a tissue-specific, developmental-specific, or temporally controlled manner. Other methods includes screening methods and therapeutic methods. |