发明名称 Stable pharmaceutical compositions of platinum (II) antitumour agents
摘要 A pharmaceutical composition comprising a platinum (II) complex compound in n aqueous solvent. The pharmaceutical composition is prepared by the essential steps of: (i) adding a platinum (II) complex compound to an oxygen enriched aqueous solvent to obtain a solution; (ii) Sterilizing the solution (iii) Filling the sterilizedsolution of step (ii) into suitable containers; and (iv) Sealing the containers. The oxygen enriched aqueous solvent is obtained by purging or bubbling of a gas into an aqueous solvent for 30 to 150 minutes. A device for preparing the pharmaceutical composition is illustrated in FIG. 1. The composition is used for treatment of a human or an animal cancerous disease by the administration of pharmaceutical compositions of platinum (II) complex compounds as per the claim 1, to the human or animal in need of said treatment.
申请公布号 US2006216360(A1) 申请公布日期 2006.09.28
申请号 US20050245141 申请日期 2005.10.06
申请人 DABUR PHARMA LTD. 发明人 UPADHYAY SATISH C.;PANANCHUKUNNATH MANOJ K.;KUMAR DINESH;SINGH AJEET K.;MUKHERJEE RAMA;BURMAN ANAND C.
分类号 A61K33/24;A61K31/282 主分类号 A61K33/24
代理机构 代理人
主权项
地址