发明名称 |
Cross-beta structures on microbial organisms |
摘要 |
The present invention discloses the use of a protease inhibitor in the preparation of a medicament for the treatment of microbial infections. The invention further discloses the use of a compound binding to a cross-ß structure or an antibody specific for a cross-ß structure in the preparation of a medicament for the treatment of microbial infections. The invention further discloses methods for attenuating microbial pathogens by deleting at least part of a gene encoding a cross-ß structure forming protein. The invention also discloses antimicrobial composition, and a kit for detecting microbial contamination in a solution or a substance. |
申请公布号 |
EP1704867(A1) |
申请公布日期 |
2006.09.27 |
申请号 |
EP20050075656 |
申请日期 |
2005.03.18 |
申请人 |
CROSSBETA BIOSCIENCES B.V. |
发明人 |
GEBBINK, MARTIJN FRANS BEN GERARD;BOUMA, BAREND;WOESTEN, HERMAN ABEL BERNARD |
分类号 |
A61K38/55;A61K38/48;A61K39/02;A61K39/40;C12Q1/37;C12Q1/56 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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