| 摘要 |
A compound represented by the following general formula (1): Q<1>-Q<2>-T<0>-N(R<1>)-Q<3>-N(R<2>)-T<1>-Q<4> (1) wherein R<1> and R<2> represent each hydrogen, etc.; Q<1> represents optionally substituted and saturated or unsaturated 5- to 6-membered cyclic hydrocarbyl, etc.; Q<2> represents a single bond, etc.; Q<3> represents a group of the following formula: (wherein Q<5> represent C1-8 alkylene,etc.); and T<0> and T<1> represent each carbonyl, etc.; its salt, solvates thereof or N-oxides of the same. These compounds are useful as preventives and/or remedies for cerebral infarction, cerebralembolism, myocardial infarction, angina, pulmonary infarction, pulmonary embolism, Burger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombosis after artificial valve/joint replacement, thrombosis and reocclusion after reconstructing blood circulation, systemic inflammatory response syndrome (SIRS), multiorgan dysfunction syndrome (MODS), thrombosis in extracorporeal circulation and blood coagulation in blood collection. |
