| 发明名称 |
Adeno-associated virus-mediated delivery of GDNF to skeletal muscles |
| 摘要 |
Compositions and methods for delivering GDNF to skeletal muscles to result in a therapeutic effect are disclosed. The compositions and methods use adeno-associated virus (AAV)-based gene delivery systems. The methods are useful for treating motoneuron diseases, such as amyotrophic lateral sclerosis (ALS).
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| 申请公布号 |
US7112321(B2) |
申请公布日期 |
2006.09.26 |
| 申请号 |
US20020327620 |
申请日期 |
2002.12.19 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
WANG LIJUN;MURAMATSU SHIN-ICHI;NAKANO IMAHARU;MIZUKAMI HIROAKI;OZAWA KEIYA |
| 分类号 |
A61K48/00;A61K35/76;A61P25/14;C07K14/475;C12N15/864 |
主分类号 |
A61K48/00 |
| 代理机构 |
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