THERAPIES FOR CHRONIC RENAL FAILURE

摘要

The present invention provides methods for the treatment, and pharmaceutical s for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain proteins of, or based upon, the osteogenic protein/bone morphogenetic protei n (OP/BMP) family within the TGF-.beta. superfamily of proteins.