发明名称 |
Compositions and methods for enhancing oligonucleotide-mediated gene alteration |
摘要 |
Composition and methods for enhancing oligonucleotide-directed nucleic acid sequence alteration in vivo, ex vivo and in vitro are presented. These methods and compositions involve cells and cell-free extracts with altered levels or activities of a protein from the RAD52 epistasis group, the mismatch repair group and/or the excision repair group.
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申请公布号 |
US7112405(B2) |
申请公布日期 |
2006.09.26 |
申请号 |
US20020260375 |
申请日期 |
2002.09.27 |
申请人 |
UNIVERSITY OF DELAWARE |
发明人 |
KMIEC ERIC B.;RICE MICHAEL C.;LIU LI |
分类号 |
C12Q1/68;A61K38/00;C12N15/10;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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