| 发明名称 |
ATTENUATED MICROORGANISMS FOR THE TREATMENT OF INFECTION |
| 摘要 |
A Salmonella microorganism has an attenuating mutation which disrupts the expression of an apparatus gene located within the Spi2 pathogenicity island, and an auxotrophic mutation. The microorganism therefore has a double mutation which helps prevent reactivity of the microorganism while maintaining the effectiveness of the microorganism to elicit an immune response.
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| 申请公布号 |
KR20060101563(A) |
申请公布日期 |
2006.09.25 |
| 申请号 |
KR20067018279 |
申请日期 |
2006.09.07 |
| 申请人 |
MICROSCIENCE LIMITED |
发明人 |
DOUGAN GORDON;SANTANGELO JOSEPH DAVID;HOLDEN DAVID WILLIAM;SHEA JACQUELINE ELIZABETH;HINDLE ZOE |
| 分类号 |
C12N1/21;C12N15/09;A61K35/74;A61K39/112;A61K48/00;A61P31/04;A61P43/00;C07K14/255;C12N15/31;C12R1/42 |
主分类号 |
C12N1/21 |
| 代理机构 |
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