| 发明名称 |
Erastin and erastin binding proteins, and uses thereof |
| 摘要 |
The invention relates to methods of screening for binding partners, especially binding partners essential for the biological activity of erastin (e.g. VDACs such as VDAC3). The invention also provides reagents and methods for effective killing of cancer cells with erastin and related compounds or derivatives.
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| 申请公布号 |
US2006211683(A1) |
申请公布日期 |
2006.09.21 |
| 申请号 |
US20060340430 |
申请日期 |
2006.01.25 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
SELLIAH ROBERT;QI LONGWU;ROBBINS PAUL B.;SAHASRABUDHE SUDHIR R.;STOCKWELL BRENT R.;VENKAT RAJ G. |
| 分类号 |
A61K31/551;A61K31/517;C07D403/02 |
主分类号 |
A61K31/551 |
| 代理机构 |
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