摘要 |
<p>This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disease, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, Crohn's disease, a respiratory disease, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.</p> |
申请人 |
AMOREPACIFIC CORPORATION;SUH, YOUNG-GER;KIM, HEE-DOO;OH, UH TAEK;PARK, HYEUNG-GEUN;SEUNG, HO SUN;PARK, SEOL RIN;KIM, JOO HYUN;NAM, YOUN HEE;PARK, YOUNG-HO;SHIN, SONG SEOK;KIM, SUN-YOUNG;KIM, JIN KWAN;JEONG, YEON SU;JOO, YUNG HYUP;LEE, KI-WHA;CHOI, JIN KYU;LIM, KYUNG MIN;KOH, HYUN JU;MOH, JOO HYUN;WOO, BYOUNG YOUNG |
发明人 |
SUH, YOUNG-GER;KIM, HEE-DOO;OH, UH TAEK;PARK, HYEUNG-GEUN;SEUNG, HO SUN;PARK, SEOL RIN;KIM, JOO HYUN;NAM, YOUN HEE;PARK, YOUNG-HO;SHIN, SONG SEOK;KIM, SUN-YOUNG;KIM, JIN KWAN;JEONG, YEON SU;JOO, YUNG HYUP;LEE, KI-WHA;CHOI, JIN KYU;LIM, KYUNG MIN;KOH, HYUN JU;MOH, JOO HYUN;WOO, BYOUNG YOUNG |