发明名称 |
Co-precipitated amorphous losartan and dosage forms comprising the same |
摘要 |
The technical field of the invention relates to spray dried, co-precipitate amorphous losartan dosage forms that are stable over time and processes for their preparation. The processes stabilize the amorphous losartan. The process includes preparing an aqueous solution of losartan and one or more hydrophilic polymers; and spray drying the aqueous solution of losartan and one or more hydrophilic polymers to form a mixture. The amorphous losartan and one or more hydrophilic polymers are co-precipitated from the aqueous solution.
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申请公布号 |
US2006210620(A1) |
申请公布日期 |
2006.09.21 |
申请号 |
US20040542587 |
申请日期 |
2004.01.21 |
申请人 |
KUMRA PANNANCHUKUNNATH M;MANIKANDAN RAMALINGAM;SINGH ROMI B;NAGAPRASAD VISHNUBHOTLA |
发明人 |
KUMRA PANNANCHUKUNNATH M.;MANIKANDAN RAMALINGAM;SINGH ROMI B.;NAGAPRASAD VISHNUBHOTLA |
分类号 |
A61K31/41;A61K9/16;A61K9/20;A61K9/48;A61K31/4174;A61K31/4178 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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