摘要 |
There are presented compounds of the formula or pharmaceutically acceptable salts thereof, wherein Y<SUB>1</SUB>, Y<SUB>2</SUB>, X<SUB>1</SUB>, X<SUB>2</SUB>, X<SUB>3 </SUB>and R are as described in this application. These compounds are believed to inhibit MDM2-p53 interaction and as such the compounds will have anti-hyperproliferative cellular activity.
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