The present invention relates generally to ophthamological drugs. More specifically, the invention relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma.
申请公布号
WO2006047466(A3)
申请公布日期
2006.09.21
申请号
WO2005US38287
申请日期
2005.10.21
申请人
DUKE UNIVERSITY;TOONE, ERIC, J.;EPSTEIN, DAVID, L.;CHALLA, PRATAP;SNYDER, PHILLIP, W.;CHEN, XIN;DELONG, MITCHELL, A.