发明名称 |
CRYSTALLINE FORMS OF A BIPHENYL COMPOUND |
摘要 |
The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder. |
申请公布号 |
WO2006099165(A1) |
申请公布日期 |
2006.09.21 |
申请号 |
WO2006US08644 |
申请日期 |
2006.03.09 |
申请人 |
THERAVANCE, INC.;AXT, SABINE;CHURCH, TIMOTHY J.;MALATHONG, VIENGKHAM |
发明人 |
AXT, SABINE;CHURCH, TIMOTHY J.;MALATHONG, VIENGKHAM |
分类号 |
C07D211/46;A61K31/45;A61P11/06 |
主分类号 |
C07D211/46 |
代理机构 |
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地址 |
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