发明名称 |
ATM kinase compositions and methods |
摘要 |
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
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申请公布号 |
US7108992(B2) |
申请公布日期 |
2006.09.19 |
申请号 |
US20020307077 |
申请日期 |
2002.11.27 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
KASTAN MICHAEL B.;BAKKENIST CHRISTOPHER |
分类号 |
C07K16/40;A61K31/4706;A61K31/675;C12Q1/48;G01N33/573;G01N33/68 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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