发明名称 Benzoxathiepine derivatives and their use as medicines
摘要 The invention concerns 3-arylthio-propyl-amino-3,4-dihydro-2H-1,5-aryloxathiepin derivatives of general formula (I), wherein: R1 and R2, identical or different, represent a hydrogen atom, a fluorine atom or a chlorine atom, a hydroxy group, an alkyl, cyclopropyl, alkoxy, cyclopropoxy radical or when they occupy adjacent positions, form with the carbon atoms bearing them a carbon-containing cycle or an oxygen-containing heterocycle with five non-aromatic rings; R3 represents an alkyl radical, a hydroxy group or a methoxy radical; R4 represents a hydrogen atom or a methyl radical; and R5 and R6, identical or different represent a hydrogen atom, an alkyl, alkoxy, alkylthio, alkylamino radical, or the groups OR4 and R5 form with the carbons which bear them a non-aromatic heterocycle with five or six rings containing at least an oxygen atom; and their pharmaceutically acceptable additions salts
申请公布号 US7109234(B2) 申请公布日期 2006.09.19
申请号 US20030472728 申请日期 2003.09.22
申请人 PIERRE FABRE MEDICAMENT 发明人 VACHER BERNARD;CASTAN-CUISAT FLORENCE;JOHN GARETH;LEGRAND BRUNO
分类号 A61K31/38;A61K31/39;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P25/00;A61P25/04;A61P25/08;A61P25/28;A61P43/00;C07C319/20;C07C323/12;C07C323/22;C07D327/00;C07D327/02;C07D411/12 主分类号 A61K31/38
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