发明名称 Compositions and methods comprising long-chain, straight-chain 2-amino-3-hydroxyalkanes
摘要 Investigation of the activity of extracts of the clam Spisula polynyma has led to antitumor long-chain, straight-chain alkane or alkene compounds which have a 2-amino group and a 3-hydroxy group. The present invention is directed to compositions and methods comprising an isolated and purified long-chain, straight-chain 2-amino-3-hydroxyalkane, or prodrug thereof, and a pharmaceutically acceptable carrier, wherein the carbon chain in the long-chain, straight-chain 2-amino-3-hydroxyalkane is C<SUB>16</SUB>-C<SUB>24</SUB>.
申请公布号 US7109244(B2) 申请公布日期 2006.09.19
申请号 US20030693174 申请日期 2003.10.23
申请人 RINEHART KENNETH L;WARWICK ROBERT A;AVILA JESUS;FREGEAU GALLAGHER NANCY L;GRAVALOS DOLORES GARCIA;FAIRCLOTH GLYNN T 发明人 RINEHART KENNETH L.;WARWICK ROBERT A.;AVILA JESUS;FREGEAU GALLAGHER NANCY L.;GRAVALOS DOLORES GARCIA;FAIRCLOTH GLYNN T.
分类号 A61K31/13;A61K35/56;C07C213/00;C07C215/00;C07C217/00 主分类号 A61K31/13
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