发明名称 |
Compositions and methods comprising long-chain, straight-chain 2-amino-3-hydroxyalkanes |
摘要 |
Investigation of the activity of extracts of the clam Spisula polynyma has led to antitumor long-chain, straight-chain alkane or alkene compounds which have a 2-amino group and a 3-hydroxy group. The present invention is directed to compositions and methods comprising an isolated and purified long-chain, straight-chain 2-amino-3-hydroxyalkane, or prodrug thereof, and a pharmaceutically acceptable carrier, wherein the carbon chain in the long-chain, straight-chain 2-amino-3-hydroxyalkane is C<SUB>16</SUB>-C<SUB>24</SUB>.
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申请公布号 |
US7109244(B2) |
申请公布日期 |
2006.09.19 |
申请号 |
US20030693174 |
申请日期 |
2003.10.23 |
申请人 |
RINEHART KENNETH L;WARWICK ROBERT A;AVILA JESUS;FREGEAU GALLAGHER NANCY L;GRAVALOS DOLORES GARCIA;FAIRCLOTH GLYNN T |
发明人 |
RINEHART KENNETH L.;WARWICK ROBERT A.;AVILA JESUS;FREGEAU GALLAGHER NANCY L.;GRAVALOS DOLORES GARCIA;FAIRCLOTH GLYNN T. |
分类号 |
A61K31/13;A61K35/56;C07C213/00;C07C215/00;C07C217/00 |
主分类号 |
A61K31/13 |
代理机构 |
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地址 |
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