USE OF Fgf21 AS HEMATOPOIETIC FACTOR

摘要

It is intended to provide novel drugs and reagents relating to Fgf21, means useful in developing them and so on. More specifically speaking, it is intended to provide: an agent for controlling the differentiation of hematopoietic stem cells which contains a substance capable of controlling the expression or function of Fgf21; a method of controlling the differentiation of hematopoietic cells and a method of evaluating the differentiation efficiency thereof by using Fgf21; a method of screening a substance capable of controlling the differentiation of hematopoietic stem cells which comprises evaluating whether or not a test substance can control the expression or function of Fgf21; a method of identifying a polymorphism in Fgf21 capable of altering the ability to control the differentiation of hematopoietic stem cells; a method of evaluating the body conditions of an animal under the differentiation of hematopoietic stem cells and a diagnostic therefor; a kit which contains a substance capable of controlling the expression or function of Fgf21; and so on.