INFECTIOUS, CHIMERIC HEPATITIS C VIRUS, METHODS OF PRODUCING THE SAME AND METHODS OF USE THEREOF

摘要

The present invention provides infectious recombinant Hepatitis C Viruses (HCV), and vectors, cells and animals comprising the same. The present invention provides methods of producing infectious recombinant HCV, and their use in identifying anti-HCV therapeutic agents, as well as sequences of HCV associated with HCV pathogenesis.