Separation of albumin from protein samples

摘要

The present invention generally relates to methods for separating albumin from samples comprising albumin and other proteins based on the pl of albumin. More particularly, the methods relate to forming an aqueous combination comprising the sample and an anion or a cation exchange material at various pHs, agitating the combination, and separating a fraction of unbound proteins from a concentrated solids fraction comprising the ion exchange material and bound proteins.