Cytokine polypeptides and antibodies containing a signal sequence for the attachement of glycosylphosphatidylinositol

摘要

The invention relates to chimeric recombinant polypeptides, preferably therapeutic polypeptides, for example cytokines or antibodies, which are engineered to include a signal sequence for the attachment of glycosylphosphatidylinositol; cells expressing said polypeptides and methods to manufacture said polypeptides.