发明名称 LIPOSOMES
摘要 This invention provides a liposome having a drug included therein, which has active targeting property and ensured stability in blood and can be used effectively in the diagnosis and/or treatment of diseases, particularly renal diseases, that accompany production of proteoglycan, comprising (1) a basic compound which takes positive charge within a physiological pH range, (2) a lipid derivative of a hydrophilic polymer and (3) a lipid which constitutes the liposome, as its membrane constituting components, wherein their constituting ratios are from 1 to 20 mol% of (1) based on (3) and from 0.2 to 5 mol% of (2) based on the total of (1) and (3).
申请公布号 EP1044679(A4) 申请公布日期 2006.09.13
申请号 EP19990951210 申请日期 1999.11.02
申请人 TERUMO KABUSHIKI KAISHA 发明人 KAWAHARA, KAZUO;USHIJIMA, HIDETO;UCHIYAMA, HIDEKI;KIMURA, JUNJI;KASUKAWA, HIROAKI
分类号 A61K9/127 主分类号 A61K9/127
代理机构 代理人
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