Method for the production of S-adenosylmethionine by fermentation

摘要

Microorganism strain (A) that secretes S-adenosylmethionine (SAM) has increased activity on the cmr (mdfA) gene product (I). Independent claims are also included for: (1) plasmid that contains the SAM-synthetase gene (II) and a cmr (mdfA) gene (III), with a promoter; (2) preparing (A) by introducing the plasmid of (1) into a parent strain; and (3) preparation of SAM by cultivating (A) in a fermentation medium such that SAM is secreted into the medium. ACTIVITY : Antidepressant; Hepatotropic; Antiarthritic. No biological data given. MECHANISM OF ACTION : SAM is a methyl group donor. No biological data given.