发明名称 Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates
摘要 A monoclonal antibody, and a cell line capable of producing the same, has been produced with the ability to detect the primary metabolites generated from the pyrolysis of smokeable, or "crack", cocaine. This monoclonal antibody, while being highly specific for anhydroecgonine methyl ester (AEME) and ecgonidine (ECD), does not cross-react at a significant level with the primary cocaine metabolites of powdered or injected cocaine. Also, crack cocaine conjugates capable of evoking an immune response in animals have been produced.
申请公布号 US7105643(B2) 申请公布日期 2006.09.12
申请号 US20030629749 申请日期 2003.07.30
申请人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ATTORNEY GENERAL OF THE DEPT. OF JUSTICE 发明人 LU NATALIE T.
分类号 C07K16/44;C07K1/13;C12N5/18;C12N5/20;G01N33/531 主分类号 C07K16/44
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